![]() ![]() doi: 10.1093/humrep/deaa284.Telomeres are the protective structures located at the ends of linear chromosomes. Undetectable viral RNA in oocytes from SARS-CoV-2 positive women. doi: 10.1093/humrep/deh818.īarragan M., Guillén J.J., Martin-Palomino N., Rodriguez A., Vassena R. Resolving methodological and clinical issues in the design of efficacy trials in assisted reproductive technologies: A mini-review. In Vitro Fertilization and Early Pregnancy Outcomes After Coronavirus Disease 2019 (COVID-19) Vaccination. The Impact of the Coronavirus Disease 19 Pandemic on Early Pregnancy Outcomes Among Patients Undergoing In Vitro Fertilization Treatment. Mrna Covid-19 Vaccines Do Not Compromise Implantation of Euploid Embryos. All rights reserved.Īharon D., Canon C.M., Hanley W.J., Lee J.A., Lederman M.A., Stein D.E., Copperman A.B. The potential negative effect of the vaccine on endometrial receptivity and reproductive outcomes is reassuring for patients in the process of undergoing assisted reproductive treatment.ĬOVID-19 vaccines, embryo implantation, clinical pregnancy rate, assisted reproductive techniques SARS-CoV-2 Single embryo transfer.Ĭopyright © 2022 Reproductive Healthcare Ltd. The administration of mRNA vaccines against COVID-19 had no effect on endometrial receptivity and embryo implantation, regardless of the number of doses and time interval from vaccination to embryo transfer. In addition, no differences were found according to the time interval from vaccination to embryo transfer. Within the vaccinated group, women who had received one or two doses also had similar outcomes. ![]() Similar CPR and SIR were found between non-vaccinated and vaccinated women, and the odds ratio for both outcomes was not statistically significant after being controlled for potential confounders (OR 0.937, 95% CI 0.695 to 1.265 and OR 0.910, 95% CI 0.648 to 1.227 respectively). Lastly, vaccinated women were divided into quartiles according to the time from last dose to embryo transfer. These outcomes were compared between non-vaccinated and vaccinated women, and women who had received one and two doses. The main outcomes were clinical pregnancy rate (CPR) and sustained implantation rate (SIR) per embryo transfer. Tulipán, Móstoles Madrid 28933, Spain.ĭoes the COVID-19 vaccination affect endometrial receptivity after single euploid embryo transfer, measured by sustained implantation rate?Ī retrospective cohort study analysing two groups of single euploid embryo transfers using own oocytes: one historical cohort of 3272 transfers 1 year before the pandemic and one comprising 890 transfers in women previously vaccinated with mRNA vaccines against severe acute respiratory syndrome coronavirus 2. del Talgo, 68, Madrid 28023, Spain University Rey Juan Carlos, C. 5 IVI Foundation, Instituto de Investigación Sanitaria La Fe, Valencia, Spain, Avenida Fernando Abril Martorell, 106 - Biopolo, Torre A, Planta 1ª, Valencia 46026, Spain Department of Reproductive Medicine, IVIRMA Madrid, Av.4 IVI Foundation, Instituto de Investigación Sanitaria La Fe, Valencia, Spain, Avenida Fernando Abril Martorell, 106 - Biopolo, Torre A, Planta 1ª, Valencia 46026, Spain.3 IVI Foundation, Instituto de Investigación Sanitaria La Fe, Valencia, Spain, Avenida Fernando Abril Martorell, 106 - Biopolo, Torre A, Planta 1ª, Valencia 46026, Spain Department of Reproductive Medicine, IVIRMA Valencia, Plaza de la Policia Local 3, Valencia 46015, Spain.Electronic address: 2 Department of Reproductive Medicine, IVIRMA Roma, Largo Ildebrando Pizzetti, 1/Piano 1 Interno 2, Rome 00197, Italy IVI Foundation, Instituto de Investigación Sanitaria La Fe, Valencia, Spain, Avenida Fernando Abril Martorell, 106 - Biopolo, Torre A, Planta 1ª, Valencia 46026, Spain. Hernâni Monteiro, Porto 4200-319, Portugal. 1 Department of Reproductive Medicine, IVIRMA Lisboa, H 1- 9ª, Avenida Infante Dom Henrique 333, Lisbon 1800-282, Portugal Faculty of Medicine, University of Porto, Alameda Prof. ![]()
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